SUMO3 Antibody
| Code | Size | Price |
|---|
| PSI-5757-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5757-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SUMO3 Antibody: SMT3A, Smt3B, SMT3H1, SUMO-3, SMT3B, Small ubiquitin-related modifier 3, SMT3 homolog 1
Application Note:
SUMO3 antibody can be used for detection of SUMO3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
SUMO3 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (Sumo-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, which is a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. All SUMO proteins localize to the nucleus and are covalently conjugated, affecting protein structure, function and interactions. SUMO2 and 3 are 96% identical and are more mobile within nucleus relative to SUMO1. Specific functional differences between SUMO1 and SUMO2 and 3 remain to be identified.
Background References:
- Kamitani T, Kito K, Nguyen HP, et al. Characterization of a second member of the sentrin family of ubiquitin-like proteins. J. Biol. Chem.1998;273:11349-53.
- Kim KI, Baek SH, and Chung CH. Versatile protein tag, SUMO: its enzymology and biological function. J. Cell. Physiol.2002; 191: 257-68.
- Su H and Li SS. Molecular features of human ubiquitin-like SUMO genes and their encoded proteins. Gene2002; 296: 65.
- Saitoh H and Hinchey J. Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3. J. Biol. Chem.2000; 275:6252-8.
Buffer:
SUMO3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SUMO3 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human SUMO3.
The immunogen is located within the last 50 amino acids of SUMO3.
The immunogen is located within the last 50 amino acids of SUMO3.
NCBI Gene ID #:
6612
NCBI Official Name:
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
NCBI Official Symbol:
SUMO3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_008867
Protein GI Number:
48928058
Purification:
SUMO3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
P55854
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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