SESTD1 Antibody
| Code | Size | Price |
|---|
| PSI-5877-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5877-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SESTD1 Antibody: SOLO, SOLO, SEC14 domain and spectrin repeat-containing protein 1, Huntingtin-interacting protein-like protein
Application Note:
SESTD1 antibody can be used for detection of SESTD1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
SESTD1 Antibody: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.
Background References:
- Sato T and Mishina M. Representational difference analysis, high-resolution physical mapping, and transcript identification of the zebrafish genomic region for a motor behavior. Genomics2003; 82:218-29.
- Miehe S, Bieberstein A, Arnold I, et al. The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5. J. Biol. Chem.2010; 285:12426-34.
Buffer:
SESTD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SESTD1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SESTD1.
The immunogen is located within the last 50 amino acids of SESTD1.
The immunogen is located within the last 50 amino acids of SESTD1.
NCBI Gene ID #:
91404
NCBI Official Name:
SEC14 and spectrin domains 1
NCBI Official Symbol:
SESTD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_835224
Protein GI Number:
188528641
Purification:
SESTD1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
Swissprot #:
Q86VW0
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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