SH3RF2 Antibody
| Code | Size | Price |
|---|
| PSI-5887-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5887-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SH3RF2 Antibody: HEPP1, POSHER, RNF158, PPP1R39, Putative E3 ubiquitin-protein ligase SH3RF2, Heart protein phosphatase 1-binding protein, HEPP1
Application Note:
SH3RF2 antibody can be used for detection of SH3RF2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
SH3RF2 Antibody: Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.
Background References:
- Ernst C, Sequeira A, Klempan, et al. Confirmation of region-specific patterns of gene expression in the human brain. Neurogenetics2007; 8:219-24.
- Chen CY, Lai NS, Yang JJ, et al. FLJ23654 encodes a heart protein phosphatase 1-binding protein (Hepp1). Biochem. Biophys. Res. Commun.2010; 391:698-702.
Buffer:
SH3RF2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SH3RF2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SH3RF2.
The immunogen is located within the last 50 amino acids of SH3RF2.
The immunogen is located within the last 50 amino acids of SH3RF2.
NCBI Gene ID #:
153769
NCBI Official Name:
SH3 domain containing ring finger 2
NCBI Official Symbol:
SH3RF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_689763
Protein GI Number:
222446607
Purification:
SH3RF2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
Swissprot #:
Q8TEC5
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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