NOD6 Antibody

ProSci
Product Code: PSI-5955
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-5955-0.02mg0.02mg£150.00
Quantity:
PSI-5955-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of NOD6 in EL4 cell lysate with NOD6 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
2 / 3
Immunohistochemistry of NOD6 in human testis tissue with NOD6 antibody at 10 μg/mL.
3 / 3
Immunofluorescence of NOD6 in human testis tissue with NOD6 antibody at 20 μg/mL.

Western blot analysis of NOD6 in EL4 cell lysate with NOD6 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
Immunohistochemistry of NOD6 in human testis tissue with NOD6 antibody at 10 μg/mL.
Immunofluorescence of NOD6 in human testis tissue with NOD6 antibody at 20 μg/mL.

Further Information

Additional Names:
NOD6 Antibody: NOD6, NALP9, PAN12, CLR19.1, NOD6, NACHT, LRR and PYD domains-containing protein 9, Nucleotide-binding oligomerization domain protein 6
Application Note:
NOD6 antibody can be used for detection of NOD6 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
NOD6 Antibody: NOD6, also known as NALP9, is a member of the NALP family, a group of proteins that typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD) and are involved in inflammation and innate immune defense. The bovine NOD6, which has 76% homology to its human counterpart, has been suggested to be an oocyte marker gene. In adult tissues, NALP9 mRNA is expressed exclusively in ovary and testis.
Background References:
  • Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
  • Dalbies-Tran R, Papillier P, Pennetier S, et al. Bovine mater-like NALP9 is an oocyte marker gene. Mol. Reprod. Dev.2005; 71:414-21.
  • Ponsuksili S, Brunner RM, Goldammer T, et al. Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos. Biol. Reprod.2006; 74:577-84.
Buffer:
NOD6 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (93%)
Immunogen:
NOD6 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NOD6.

The immunogen is located within amino acids 190 - 240 of NOD6.
NCBI Gene ID #:
338321
NCBI Official Name:
NLR family, pyrin domain containing 9
NCBI Official Symbol:
NLRP9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q7RTR0
Protein GI Number:
74762418
Purification:
NOD6 Antibody is affinity chromatography purified via peptide column.
Research Area:
Innate Immunity
Swissprot #:
Q7RTR0
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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