NALP11 Antibody
| Code | Size | Price |
|---|
| PSI-5969-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5969-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
NALP11 Antibody: NOD17, PAN10, NALP11, PYPAF6, PYPAF7, CLR19.6, NOD17, NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17
Application Note:
NALP11 antibody can be used for detection of NALP11 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
NALP11 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP11 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP11, it has been suggested that it has been associated with Crohn's disease.
Background References:
- Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
- Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.
- Cummings JR, Cooney RM, Clarke G, et al. The genetics of NOD-like receptors in Crohn's disease. Tiss. Antigens2010; 76:48-56.
Buffer:
NALP11 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
NALP11 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human NALP11.
The immunogen is located within the last 50 amino acids of NALP11.
The immunogen is located within the last 50 amino acids of NALP11.
NCBI Gene ID #:
204801
NCBI Official Name:
NLR family, pyrin domain containing 11
NCBI Official Symbol:
NLRP11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_659444
Protein GI Number:
194018484
Purification:
NALP11 Antibody is affinity chromatography purified via peptide column.
Research Area:
Innate Immunity
Swissprot #:
P59045
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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