PIWI-L3 Antibody
| Code | Size | Price |
|---|
| PSI-6033-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6033-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Western Blot (WB)
Documents
Further Information
Additional Names:
PIWI-L3 Antibody: HIWI3, Piwi-like protein 3
Application Note:
PIWI-L3 antibody can be used for detection of PIWI-L3 by Western blot at 1 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
PIWI-L3 Antibody: PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.
Background References:
- Sasaki T, Shiohama A, Minoshima S, et al. Identification of eight members of the Argonaute family in the human genome small star, filled. Genomics2003; 323-30.
- Thomson T and Lin H. The biogenesis and function PIWI proteins and piRNAs: progress and prospect. Annu. Rev. Cell Dev. Biol.2009; 25:355-76.
- Wang XL, Chen XM, Gao HJ, et al. Preparation and distribution of polyclonal antibodies against human PIWIL3 protein in tumor tissues. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2008; 24:714-6.
- Li L, Yu C, Gao H, et al. Argonaute proteins: potential biomarkers for human colon cancer. BMC Cancer2010; 10:38.
Buffer:
PIWI-L3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PIWI-L3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PIWI-L3.
The immunogen is located within amino acids 130 - 180 of PIWI-L3.
The immunogen is located within amino acids 130 - 180 of PIWI-L3.
NCBI Gene ID #:
440822
NCBI Official Name:
piwi-like 3 (Drosophila)
NCBI Official Symbol:
PIWIL3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001008496
Protein GI Number:
153792298
Purification:
PIWI-L3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
Swissprot #:
Q7Z3Z3
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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