LMBRD1 Antibody
| Code | Size | Price |
|---|
| PSI-6047-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6047-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
LMBRD1 Antibody: NESI, LMBD1, MAHCF, C6orf209, NESI, BM-021, CD001, MSTP044, Probable lysosomal cobalamin transporter, HDAg-L-interacting protein NESI
Application Note:
LMBRD1 antibody can be used for detection of LMBRD1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
LMBRD1 Antibody: LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).
Background References:
- Gailus S, Hohne W, Gasnier B, et al. Insights into lysosomal cobalamin trafficking: lessons learned from cblF disease. J. Mol. Med.2010; 88:459-66.
- Wang Y-S, Chang SC, Huang C, et al. Novel nuclear export signal-interacting protein, NESI, critical for the assembly of hepatitis delta virus. J. Virol.2005; 79:8113-20.
Buffer:
LMBRD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
LMBRD1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LMBRD1.
The immunogen is located within the last 50 amino acids of LMBRD1.
The immunogen is located within the last 50 amino acids of LMBRD1.
NCBI Gene ID #:
55788
NCBI Official Name:
LMBR1 domain containing 1
NCBI Official Symbol:
LMBRD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_060838
Protein GI Number:
261878497
Purification:
LMBRD1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q9NUN5
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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