STOX2 Antibody
| Code | Size | Price |
|---|
| PSI-6061-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6061-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
STOX2 Antibody: KIAA1392, Storkhead-box protein 2
Application Note:
STOX2 antibody can be used for detection of STOX2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
STOX2 Antibody: The Storkhead box protein 2 (STOX2) is the only known paralog to STOX1, a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. STOX2 has been suggested to be part of a molecular profile unique to stem cells, and its mRNA may be part of a transcriptional profile observed with increased inflammatory response to air pollutants. Decreased STOX2 expression levels in decidua are also correlated with preeclampsia, suggesting STOX2 may play a role in the pathophysiology of preeclampsia.
Background References:
- van Dijk M, van Bezu J, Chim SS, et al. Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family. Nat. Genet.2005; 37:514-9.
- Kivinen K, Peterson H, Hiltunen L, et al. Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample. Eur. J. Hum. Genet.2007; 15:494-7.
- Thomas S, Thomas M, Wincker P, et al. Human neural crest cells display molecular and phenotypic hallmarks of stem cells. Hum. Mol. Genet.2008; 17:3411-25.
- Fedulov AV, Leme A, Yang Z, et al. Pulmonary exposure to particles during pregnancy causes increased neonatal asthma susceptibility. Am. J. Respir. Cell Mol. Biol.2008; 38:57-67.
Buffer:
STOX2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
STOX2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human STOX2.
The immunogen is located within the last 50 amino acids of STOX2.
The immunogen is located within the last 50 amino acids of STOX2.
NCBI Gene ID #:
56977
NCBI Official Name:
storkhead box 2
NCBI Official Symbol:
STOX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_064610
Protein GI Number:
55742730
Purification:
STOX2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
Swissprot #:
Q9P2F5
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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