ZIP8 Antibody

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ProSci
Product Code: PSI-6095
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6095-0.02mg0.02mg£150.00
Quantity:
PSI-6095-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of ZIP8 in human spleen tissue lysate with ZIP8 antibody at (A) 1 and (B) 2 μg/mL.
2 / 3
Immunohistochemistry of ZIP8 in human spleen tissue with ZIP8 antibody at 5 μg/mL.
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Immunofluorescence of ZIP8 in human spleen tissue with ZIP8 antibody at 20 μg/mL.
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Western blot analysis of ZIP8 in human spleen tissue lysate with ZIP8 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of ZIP8 in human spleen tissue with ZIP8 antibody at 5 μg/mL.
Immunofluorescence of ZIP8 in human spleen tissue with ZIP8 antibody at 20 μg/mL.

Documents

Further Information

Additional Names:
ZIP8 Antibody: ZIP8, PP3105, BIGM103, LZT-Hs6, ZIP8, Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein
Application Note:
ZIP8 antibody can be used for detection of ZIP8 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
ZIP8 Antibody: The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.
Background References:
  • Dufner-Beattie J, Langmade SJ, Wang F, et al. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem.2003; 278:50142-50.
  • Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.
  • Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.
  • Dalton TP, He L, Wang B, et al. Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc. Natl. Acad. Sci. USA2005; 102:3401-6.
Buffer:
ZIP8 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse: (89%), Rat: (89%)
Immunogen:
ZIP8 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human ZIP8.

The immunogen is located within the last 50 amino acids of ZIP8.
NCBI Gene ID #:
64116
NCBI Official Name:
solute carrier family 39 (zinc transporter), member 8
NCBI Official Symbol:
Slc39a8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_071437
Protein GI Number:
205830403
Purification:
ZIP8 Antibody is affinity chromatography purified via peptide column.
Research Area:
Immunology
SPECIFICITY:
ZIP8 antibody is predicted to not cross-react with other ZIP family members.
Swissprot #:
Q9C0K1
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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