ZIP9 Antibody

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ProSci
Product Code: PSI-6097
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6097-0.02mg0.02mg£150.00
Quantity:
PSI-6097-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of ZIP9 in HepG2 cell lysate with ZIP9 antibody at (A) 1 and (B) 2 μg/mL.
2 / 3
Immunohistochemistry of ZIP9 in human brain tissue with ZIP9 antibody at 2.5 μg/mL.
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Immunofluorescence of ZIP9 in human brain tissue with ZIP9 antibody at 20 μg/mL.
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Western blot analysis of ZIP9 in HepG2 cell lysate with ZIP9 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of ZIP9 in human brain tissue with ZIP9 antibody at 2.5 μg/mL.
Immunofluorescence of ZIP9 in human brain tissue with ZIP9 antibody at 20 μg/mL.

Documents

Further Information

Additional Names:
ZIP9 Antibody: ZIP9, ZIP-9, ZIP9, UNQ714/PRO1377, Zinc transporter ZIP9, Solute carrier family 39 member 9
Application Note:
ZIP9 antibody can be used for detection of ZIP9 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
ZIP9 Antibody: The zinc transporter ZIP9, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP9 is a multipass membrane protein that belongs to the ZIP transporter subfamily I. It is located at the trans-Golgi network regardless of zinc presence and is thought to be a zinc homeostasis regulator acting in the secretory pathway without significantly altering cytosolic zinc homeostasis.
Background References:
  • Dufner-Beattie J, Langmade SJ, Wang F, et al. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem.2003; 278:50142-50.
  • Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.
  • Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.
  • Matsuura W, Yamazaki T, Yamaguchi-Iwai Y, et al. SLC39A9 (ZIP9) regulates zinc homeostasis in the secretory pathway: characterization of the ZIP subfamily protein in vertebrate cells. Biosci. Biotechnol. Biochem.2009; 73:1142-1148.
Buffer:
ZIP9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat: (89%)
Immunogen:
ZIP9 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human ZIP9.

The immunogen is located within amino acids 70 - 120 of ZIP9.
NCBI Gene ID #:
55334
NCBI Official Name:
solute carrier family 39 (zinc transporter), member 9
NCBI Official Symbol:
Slc39a9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_060845
Protein GI Number:
237874617
Purification:
ZIP9 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
ZIP9 antibody is predicted to not cross-react with other ZIP family members.
Swissprot #:
Q9NUM3
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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