FBXL16 Antibody
| Code | Size | Price |
|---|
| PSI-6165-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6165-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
FBXL16 Antibody: Fbl16, C16orf22, c380A1.1, FBL16, F-box and leucine-rich repeat protein 16
Application Note:
FBXL16 antibody can be used for detection of FBXL16 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
FBXL16 Antibody: FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F-box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.
Background References:
- Martin J, Han C, Gordon LA, et al. The sequence and analysis of duplication-rich human chromosome 16. Nature2004; 432:988-94.
- Jin J, Cardozo T, Lovering RC, et al. Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev.2004; 18:2573-80.
- Sato K, Kusama Y, Tategu M, et al. FBXL16 is a novel E2F1-regulated gene commonly upregulated in p16INK4A- and p14ARF-silenced HeLa cells. Int. J. Oncol.2010; 36:479-90.
Buffer:
FBXL16 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
FBXL16 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human FBXL16.
The immunogen is located within the last 50 amino acids of FBXL16.
The immunogen is located within the last 50 amino acids of FBXL16.
NCBI Gene ID #:
146330
NCBI Official Name:
F-box and leucine-rich repeat protein 16
NCBI Official Symbol:
FBXL16
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_699181
Protein GI Number:
289666746
Purification:
FBXL16 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
SPECIFICITY:
FBXL16 antibody is predicted to not cross-react with other F-box protein family members.
Swissprot #:
Q8N461
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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