OGFOD2 Antibody
| Code | Size | Price |
|---|
| PSI-6179-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6179-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
OGFOD2 Antibody: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
Application Note:
OGFOD2 antibody can be used for detection of OGFOD2 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
OGFOD2 Antibody: OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
Background References:
- Saito K, Adachi N, Koyama H et al. OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling. FEBS Lett. 2010; 584:3340-7.
- Wehner KA, Schutz S and Sarnow P. OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress. Mol. Cell. Biol. 2010; 30:2006-16.
- Marina O, Hainz U, Biernacki MA, et al. Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens. Cancer Res. 2010; 70:1344-55.
Buffer:
OGFOD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
OGFOD2 antibody was raised against a 17 amino acid synthetic peptide near the center of human OGFOD2.
The immunogen is located within amino acids 140 - 190 of OGFOD2.
The immunogen is located within amino acids 140 - 190 of OGFOD2.
NCBI Gene ID #:
79676
NCBI Official Name:
2-oxoglutarate and iron-dependent oxygenase domain containing 2
NCBI Official Symbol:
OGFOD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_078899
Protein GI Number:
13375846
Purification:
OGFOD2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Apoptosis
SPECIFICITY:
OGFOD2 antibody is predicted to not cross-react with other TPA1 protein family members. At least three isoforms are known to exist; this antibody will only detect the two larger isoforms.
Swissprot #:
Q6N063
User NOte:
Optimal dilutions for each application to be determined by the researcher.
Related Products
| Product Name | Product Code | Supplier | OGFOD2 Peptide | PSI-6179P | ProSci | Summary Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|