SLAMF9 Antibody

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ProSci
Product Code: PSI-6181
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6181-0.02mg0.02mg£150.00
Quantity:
PSI-6181-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of SLAMF9 in mouse kidney tissue lysate with SLAMF9 antibody at (A) 1 and (B) 2 μg/mL.
2 / 3
Immunohistochemistry of SLAMF9 in human kidney tissue with SLAMF9 antibody at 2.5 μg/mL.
3 / 3
Immunofluorescence of SLAMF9 in human kidney tissue with SLAMF9 antibody at 20 μg/mL.
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Western blot analysis of SLAMF9 in mouse kidney tissue lysate with SLAMF9 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of SLAMF9 in human kidney tissue with SLAMF9 antibody at 2.5 μg/mL.
Immunofluorescence of SLAMF9 in human kidney tissue with SLAMF9 antibody at 20 μg/mL.

Documents

Further Information

Additional Names:
SLAMF9 Antibody: CD2F10, CD84H1, SF2001, CD2F-10, CD84-H1, CD2F10, UNQ1938/PRO4421, SLAM family member 9, CD2 family member 10
Application Note:
SLAMF9 antibody can be used for detection of SLAMF9 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
SLAMF9 Antibody: The SLAM (signalling lymphocyte activation molecule) family is a novel group of receptors on T cells in modulating the immune response. SLAMF9, also known as CD2F-10 or CD84 homolog, is a 289 amino acid type I transmembrane protein that shares 58% identity with the mouse protein. The SLAMF9 protein is predominantly expressed in hematopoietic tissues and contains an extracellular region with only two N-linked glycosylation sites, a 20-residue transmembrane region and a highly positively charged 30-residue cytoplasmic tail, suggesting a role for SLAMF9 as an adhesion molecule. SLAMF9 is thought to function in the immune response as a coreceptor for lymphocyte activation.
Background References:
  • Veillette A and Latour S. The SLAM family of immune-cell receptors. Curr. Opin. Immunol. 2003; 15:277-85.
  • Veillette A. SLAM family receptors regulate immunity with and without SAP-related adaptors. J. Exp. Med. 2004; 199:1175-8.
  • Fennelly JA, Tiwari B, Davis SJ, et al. CD2F-10: a new member of the CD2 subset of the immunoglobulin superfamily. Immunogenetics 2001; 53:599-602.
  • Detre C, Keszei M, Romero X, et al. SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin. Immunopathol. 2010; 32:157-71.
Buffer:
SLAMF9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SLAMF9 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human SLAMF9.

The immunogen is located within the last 50 amino acids of SLAMF9.
NCBI Gene ID #:
89886
NCBI Official Name:
SLAM family member 9
NCBI Official Symbol:
SLAMF9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001139645
Protein GI Number:
226342990
Purification:
SLAMF9 Antibody is affinity chromatography purified via peptide column.
Research Area:
Immunology
SPECIFICITY:
SLAMF9 antibody is predicted to not cross-react with other SLAM protein family members.
Swissprot #:
Q96A28
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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