TMEM192 Antibody
| Code | Size | Price |
|---|
| PSI-6227-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6227-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TMEM192 Antibody: Transmembrane protein 192
Application Note:
TMEM192 antibody can be used for detection of TMEM192 by Western blot at 0.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
TMEM192 Antibody: TMEM192 is a widely expressed, four transmembrane protein that localizes to late endosomal/lysosomal membranes. This localization is mediated by two dileucine motifs present at the amino-terminus of TMEM192. A cysteine residue near the carboxy residue is responsible for disulfide bond formation in TMEM192 homodimers. Little is known about the function of this protein.
Background References:
- Schroder B, Wrocklage C, Hasilik A, et al. Molecular characterisation of ?transmembrane protein 192'(TMEM192, a novel protein of the lysosomal membrane. Biol. Chem. 2010; 391:695-704.
- Zhu H, Liang Z, and Li G. Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis. Mol. Biol. Cell 2009; 20:4720-9.
Buffer:
TMEM192 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TMEM192 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TMEM192.
The immunogen is located within amino acids 180 - 230 of TMEM192.
The immunogen is located within amino acids 180 - 230 of TMEM192.
NCBI Gene ID #:
201931
NCBI Official Name:
transmembrane protein 192
NCBI Official Symbol:
TMEM192
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001093859
Protein GI Number:
154240704
Purification:
TMEM192 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
At least two isoforms of TMEM192 are known to exist; this antibody will recognize both. TMEM192 antibody is predicted to not cross-react with other TMEM proteins.
Swissprot #:
Q8IY95
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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