TYW3 Antibody
| Code | Size | Price |
|---|
| PSI-6377-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6377-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TYW3 Antibody: C1orf171, C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3
Application Note:
TYW3 antibody can be used for detection of TYW3 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
TYW3 Antibody: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
Background References:
- Noma A and Suzuki T. Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis. Nucleic Acids Symp. Ser. (Oxf) 2006; 65-6.
- Noma A, Kirino Y, Ikeuchi Y, et al. Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J. 2006; 25:2142-54
Buffer:
TYW3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (94%), Pig: (94%)
Immunogen:
TYW3 antibody was raised against a 17 amino acid synthetic peptide near the center of human TYW3.
The immunogen is located within amino acids 160 - 210 of TYW3.
The immunogen is located within amino acids 160 - 210 of TYW3.
NCBI Gene ID #:
127253
NCBI Official Name:
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
NCBI Official Symbol:
TYW3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q6IPR3
Protein GI Number:
42734381
Purification:
TYW3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist; this antibody will detect both isoforms.
Swissprot #:
Q6IPR3
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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