ATAD3A Antibody

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ProSci
Product Code: PSI-6387
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6387-0.02mg0.02mg£150.00
Quantity:
PSI-6387-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of ATAD3A in Daudi cell lysate with ATAD3A antibody at 1 μg/mL .
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Immunocytochemistry of ATAD3A in Daudi cells with ATAD3A antibody at 20 μg/mL.
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Immunofluorescence of ATAD3A in Daudi cells with ATAD3A antibody at 20 μg/mL.
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Western blot analysis of ATAD3A in Daudi cell lysate with ATAD3A antibody at 1 μg/mL .
Immunocytochemistry of ATAD3A in Daudi cells with ATAD3A antibody at 20 μg/mL.
Immunofluorescence of ATAD3A in Daudi cells with ATAD3A antibody at 20 μg/mL.

Documents

Further Information

Additional Names:
ATAD3A Antibody: ATPase family AAA domain-containing protein 3A
Application Note:
ATAD3A antibody can be used for detection of ATAD3A by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
ATAD3A Antibody: ATAD3A is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.
Background References:
  • Patel S and Latterich M. The AAA team: related ATPases with diverse functions. Trends Cell Biol. 1998; 8:65-71.
  • Ogura T and Wilkinson AJ. AAA+ superfamily ATPases: common structure?diverse function. Genes Cells 2001; 6:575-97.
  • Hubstenberger A, Labourdette G, Baudier J, et al. ATAD3A and ATAD3B are distal 1p-located genes differentially expressed in human glioma cell lines and present in vitro anti-oncogenic and chemoresistant properties. Exp. Cell Res. 2008; 314:2870-83.
  • Fang HY, Chang CL, Hsu SH, et al. ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells. J. Cell Sci. 2010; 123:1171-80.
Buffer:
ATAD3A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ATAD3A antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATAD3A.

The immunogen is located within amino acids 110 - 160 of ATAD3A.
NCBI Gene ID #:
55210
NCBI Official Name:
ATPase family, AAA domain containing 3A
NCBI Official Symbol:
ATAD3A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q9NVI7
Protein GI Number:
283436220
Purification:
ATAD3A Antibody is affinity chromatography purified via peptide column.
Research Area:
Apoptosis
SPECIFICITY:
ATAD3A antibody is predicted to not cross-react with other ATAD protein family members. At least two isoforms are known to exist.
Swissprot #:
Q9NVI7
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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