ApoA4 Antibody
| Code | Size | Price |
|---|
| PSI-5929-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5929-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ApoA4 Antibody: Apolipoprotein A-IV, Apolipoprotein A4, Apo-AIV
Application Note:
ApoA4 antibody can be used for detection of ApoA4 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
ApoA4 Antibody: Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is an O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but evidence from several in vitro studies indicate that this apolipoprotein is involved in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
Background References:
- Karathanasis SK, Oettgen P, Haddad IA, et al. Structure, evolution, and polymorphisms of the human apolipoprotein A4 gene (APOA4). Proc. Natl. Acad. Sci. USA 1986; 83: 8457-61
- Kamboh MI, Friedlaender JS, Ahn YI, et al. A common deletion polymorphism in the apolipoprotein A4 gene and its significance in lipid metabolism. Arterioscler. Thromb. 1994; 14: 656-62
- Kronenberg F, Stuhlinger M, Trenkwalder E, et al. Low apolipoprotein A-IV plasma concentrations in men with coronary artery disease. J. Am. Coll. Cardiol. 2000; 36:751-7.
- Von Eckardstein A, Huang Y, Wu S, et al. Lipoproteins containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify cell-derived cholesterol in plasma. Arterioscler. Thromb. Vasc. Biol. 1995; 15:1755-63.
Buffer:
ApoA4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig: (100%), Bovine: (93%), Rat: (79%), Mouse: (79%)
Immunogen:
ApoA4 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ApoA4.
The immunogen is located within amino acids 320 - 370 of ApoA4.
The immunogen is located within amino acids 320 - 370 of ApoA4.
NCBI Gene ID #:
337
NCBI Official Name:
apolipoprotein A-IV
NCBI Official Symbol:
APOA4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 41 kDa
Observed: 40 kDa
Observed: 40 kDa
Protein Accession #:
NCBI accession No. AAA51744
Protein GI Number:
71773110
Purification:
ApoA4 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
P06727
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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