ApoA1 Antibody
| Code | Size | Price |
|---|
| PSI-6265-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6265-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ApoA1 Antibody: Apolipoprotein A-I, Apolipoprotein A1, Apo-AI
Application Note:
ApoA1 antibody can be used for detection of ApoA1 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in chicken samples. All other applications and species not yet tested.
Antibody validated: Western Blot in chicken samples. All other applications and species not yet tested.
Background:
ApoA1 Antibody: Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma, which is correlated with cardiovascular disease. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.
Background References:
- Zhu X, Wu G, Zeng W, et al. Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. J. Lipid Res. 2005; 46:1303-11
- Sorci-Thomas MG, Prack MM, Dashti N, et al. Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. J. Lipid Res. 1989; 30:1397-403
- Lai C-Q, Parnell LD, and Ordovas JM. The APOA1 /C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr. Opin. Lipid. 2005; 16:153-66
Buffer:
ApoA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ApoA1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ApoA1.
The immunogen is located within the last 50 amino acids of ApoA1.
The immunogen is located within the last 50 amino acids of ApoA1.
NCBI Gene ID #:
335
NCBI Official Name:
apolipoprotein A-I
NCBI Official Symbol:
APOA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P02647
Protein GI Number:
113992
Purification:
ApoA1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
P02647
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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