ApoA4 Antibody
| Code | Size | Price |
|---|
| PSI-6269-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6269-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ApoA4 Antibody: Apolipoprotein A-IV, Apolipoprotein A4, Apo-AIV
Application Note:
ApoA4 antibody can be used for detection of ApoA4 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in chicken samples. All other applications and species not yet tested.
Antibody validated: Western Blot in chicken samples. All other applications and species not yet tested.
Background:
ApoA4 Antibody: Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
Background References:
- Karathanasis SK, Oettgen P, Haddad IA, et al. Structure, evolution, and polymorphisms of the human apolipoprotein A4 gene (APOA4). Proc. Natl. Acad. Sci. 1986; 83:8457-61
- Kamboh MI, Friedlaender JS, Ahn YI et al. A common deletion polymorphism in the apolipoprotein A4 gene and tis significance in lipid metabolism. Arterioscler. Thromb. 1994; 14:656-62.
- Kronenberg F, Stuhlinger M, Trenkwalder E, et al. Low apolipoprotein A-IV plasma concentrations in men with coronary artery disease. J. Am. Coll. Cardiol., 2000; 36:751-7
- Von Eckardstein A, Huang Y, Wu S, et al. Lipoproteins containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify cell-derived cholesterol in plasma. Arterioscler Thromb Vasc Biol. 1995; 15:1755-63.
Buffer:
ApoA4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ApoA4 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of chicken ApoA4.
The immunogen is located within the last 50 amino acids of ApoA4.
The immunogen is located within the last 50 amino acids of ApoA4.
NCBI Gene ID #:
337
NCBI Official Name:
apolipoprotein A-IV
NCBI Official Symbol:
APOA4
NCBI Organism:
Gallus gallus
Physical State:
Liquid
Protein Accession #:
NP_990269
Protein GI Number:
71773110
Purification:
ApoA4 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
P06727
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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