ApoA5 Antibody
| Code | Size | Price |
|---|
| PSI-6271-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6271-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
ApoA5 Antibody:
Application Note:
ApoA5 antibody can be used for detection of ApoA5 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
ApoA5 Antibody: Apoliproprotein A-V is a protein coded by the APOA5 gene, which is highly expressed in the liver. This protein is responsible for binding to lipids in the liver and forming lipoproteins. In recent years, the gene has been used as a marker for measuring cardiovascular health as well as metabolic syndromes. The protein plays an important role in plasma triglyceride (lipid) regulation within the body. Although only expressed in the liver, APOA5 has functions both inside and outside of cells, as well as modulating triglyceride homeostasis in areas like the gut. Mutations in the APOA5 gene have up to 3 times the risk for the development of cardiovascular disease in association studies. Dietary studies support this lack of metabolic regulation by showing that any mutation in APOA5 will result in higher triglyceride levels than control groups when dieting.
Background References:
- de Luis Roman et al. Nutrients 2022, 14(12): 2427.
- Jacob et al. BMC nephrology 2022, 23, 307.
- May-Zhang et al. Biochimica et biophysica acta (BBA) - Molecular and cell biology of lipids 2022, 1867 (9): 159185.
Buffer:
ApoA5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ApoA5 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of chicken ApoA5.
The immunogen is located within the last 50 amino acids of ApoA5.
The immunogen is located within the last 50 amino acids of ApoA5.
NCBI Gene ID #:
419802
NCBI Official Name:
apolipoprotein A-V
NCBI Official Symbol:
APOA5
NCBI Organism:
gallus gallus
Physical State:
Liquid
Protein Accession #:
XP_417939
Protein GI Number:
118101989
Purification:
ApoA5 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
E1BT17
User NOte:
Optimal dilutions for each application to be determined by the researcher.
References
de Luis Roman et al. Nutrients 2022, 14(12): 2427.; Jacob et al. BMC nephrology 2022, 23, 307.; May-Zhang et al. Biochimica et biophysica acta (BBA) - Molecular and cell biology of lipids 2022, 1867 (9): 159185.
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