HDGFRP2 Antibody

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ProSci
Product Code: PSI-6411
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6411-0.02mg0.02mg£150.00
Quantity:
PSI-6411-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of HDGFRP2 in rat lung tissue lysate with HDGFRP2 antibody at 2 μg/mL .
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Immunohistochemistry of HDGFRP2 in rat liver tissue with HDGFRP2 antibody at 5 μg/mL.
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Immunofluorescence of HDGFRP2 in rat liver tissue with HDGFRP2 antibody at 20 μg/mL.
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Western blot analysis of HDGFRP2 in rat lung tissue lysate with HDGFRP2 antibody at 2 μg/mL .
Immunohistochemistry of HDGFRP2 in rat liver tissue with HDGFRP2 antibody at 5 μg/mL.
Immunofluorescence of HDGFRP2 in rat liver tissue with HDGFRP2 antibody at 20 μg/mL.

Documents

Further Information

Additional Names:
HDGFRP2 Antibody: HDGF2, HDGF2, UNQ785/PRO1604, Hepatoma-derived growth factor-related protein 2, Hepatoma-derived growth factor 2, HRP-2
Application Note:
HDGFRP2 antibody can be used for detection of HDGFRP2 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
HDGFRP2 Antibody: Hepatoma-derived growth factor-related protein 2 (HDGFRP2) is a widely expressed member of protein family that contains the HDGF related proteins 1-4 and lens epithelial derived growth factor (LEDGF). These family members show extensive homology at the amino terminus (termed the hath region). Little is known of the role of HDGFRP2, but like the related LEDGF, HDGFRP2 can bind HIV-1 integrase and stimulate HIV-1 integrase activity in vitro.
Background References:
  • El-Tahir HM, Dietz F, Dringen R, et al. Expression of Hepatoma-derived growth factor family members in the adult central nervous system. BMC Neurosci. 2006; 7:6.
  • Izumoto Y, Kuroda T, Harada H, et al. Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus. Biochem. Biophys. Res. Commun. 1997; 238:26-32
  • Cherepanov P, Devroe E, Silver PA, et al. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. J. Biol. Chem. 2004; 279:48883-92.
Buffer:
HDGFRP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken: (94%)
Immunogen:
HDGFRP2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human HDGFRP2.

The immunogen is located within amino acids 50 - 100 of HDGFRP2.
NCBI Gene ID #:
84717
NCBI Official Name:
hepatoma-derived growth factor-related protein 2
NCBI Official Symbol:
HDGFRP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAW69215
Protein GI Number:
48255931
Purification:
HDGFRP2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
SPECIFICITY:
At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members
Swissprot #:
Q7Z4V5
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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