TMEM204 Antibody
| Code | Size | Price |
|---|
| PSI-6415-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6415-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TMEM204 Antibody: CLP24, C16orf30, CLP24, UNQ6509/PRO21434, Transmembrane protein 204, Claudin-like protein 24
Application Note:
TMEM204 antibody can be used for detection of TMEM204 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
TMEM204 Antibody: Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.
Background References:
- Kearsey J, Petit S, De Oliveira C, et al. A novel four transmembrane spanning protein, CLP24. Eur. J. Biochem. 204; 271:2584-92.
- Stefaniuk M and Lukasiuk K. Cloning of expressed sequence tags (ESTs) representing putative epileptogenesis-related genes and the localization of their expression in the normal brain. Neurosci. Lett. 2010; 482:230-4
Buffer:
TMEM204 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
TMEM204 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TMEM204.
The immunogen is located within the last 50 amino acids of TMEM204.
The immunogen is located within the last 50 amino acids of TMEM204.
NCBI Gene ID #:
79652
NCBI Official Name:
transmembrane protein 204
NCBI Official Symbol:
TMEM204
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_078876
Protein GI Number:
112807182
Purification:
TMEM204 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms.
Swissprot #:
Q9BSN7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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