SPRYD4 Antibody
| Code | Size | Price |
|---|
| PSI-6407-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6407-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SPRYD4 Antibody: SPRY domain-containing protein 4
Application Note:
SPRYD4 antibody can be used for detection of SPRYD4 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
SPRYD4 Antibody: The SPRY domain-containing protein 4 (SPRYD4) is a member of a family of proteins whose sole common characteristic is the presence of a SPRY domain. SPRY domains are structural domains that were first described in the fungal Dictyostelium discoideum tyrosine kinase spore lysis A. In most systems SPRY domains provide binding sites for regulatory proteins or intramolecular binding sites that maintain the structural integrity of a protein. SPRYD4 is ubiquitously expressed and is most abundant in kidney, brain, bladder, thymus and stomach. Little is known of the function of the SPRYD4 protein.
Background References:
- Tae H, Casarotto MG, and Dulhunty AF. Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor. Eur. Biophys. J. 2009; 39:51-9.
- Zhong Z, Zhang H, Bai M, et al. Cloning and characterization of a novel human SPRYD4 gene encoding a putative SPRY domain-containing protein. DNA Seq. 2008; 19:68-72.
Buffer:
SPRYD4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (89%), Pig: (89%)
Immunogen:
SPRYD4 antibody was raised against an 18 amino acid synthetic peptide near the center of human SPRYD4.
The immunogen is located within amino acids 70 - 120 of SPRYD4.
The immunogen is located within amino acids 70 - 120 of SPRYD4.
NCBI Gene ID #:
283377
NCBI Official Name:
SPRY domain containing 4
NCBI Official Symbol:
SPRYD4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_997227
Protein GI Number:
46409324
Purification:
SPRYD4 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
SPRYD4 antibody is predicted to not cross-react with other SPRYD protein family members. At least two isoforms of SPRYD4 are known to exist; this antibody will detect both isoforms.
Swissprot #:
Q8WW59
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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