IFTLD1 Antibody

ProSci
Product Code: PSI-6447
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6447-0.02mg0.02mg£150.00
Quantity:
PSI-6447-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of IFLTD1 in rat liver tissue lysate with IFLTD1 antibody at (A) 1 and (B) 2 μg/mL.
2 / 2
Immunohistochemistry of IFTLD1 in rat liver tissue with IFTLD1 antibody at 5 μg/mL.

Western blot analysis of IFLTD1 in rat liver tissue lysate with IFLTD1 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of IFTLD1 in rat liver tissue with IFTLD1 antibody at 5 μg/mL.

Further Information

Additional Names:
IFTLD1 Antibody: PAS1C1, Intermediate filament tail domain-containing protein 1
Application Note:
IFLTD1 antibody can be used for detection of IFLTD1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.
Background:
IFTLD1 Antibody: The intermediate filament tail domain-containing protein (IFLTD1) was initially identified as a candidate gene for pulmonary adenoma susceptibility 1 gene in mice. Transcripts of the gene were only detected in mouse lung tissue from strains carrying the Pas1-susceptible allele. Expression of different alleles of this gene in lung cancer cell lines resulted in different levels of colony formation in in vitro colony formation assays, suggesting that allelic variants of this gene can modulate growth of human cancer cells.
Background References:
  • Wang M, Lemon WJ, Liu G, et al. Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Res. 2003; 63:3317-24.
  • Wang M, Futamura M, Wang Y, et al. Pasc1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus. Oncogene 2005; 24:1958-63.
  • Galbiati F, Pettinicchio A, Dragani TA, et al. Allelic effects of mouse Pas candidate genes in human lung cancer cell lines. Cancer Lett. 244:176-81.
Buffer:
IFTLD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IFLTD1 antibody was raised against an 19 amino acid synthetic peptide near the center of human IFLTD1.

The immunogen is located within amino acids 200 - 250 of IFTLD1.
NCBI Gene ID #:
160492
NCBI Official Name:
intermediate filament tail domain containing 1
NCBI Official Symbol:
IFLTD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001139200
Protein GI Number:
224593273
Purification:
IFTLD1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
SPECIFICITY:
At least four isoforms of IFLTD1 are known to exist; this antibody will detect all but isoform 4
Swissprot #:
Q8N9Z9
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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