TMEM147 Antibody
| Code | Size | Price |
|---|
| PSI-6453-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6453-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TMEM147 Antibody: NIFIE14, Transmembrane protein 147, Protein NIFIE 14
Application Note:
TMEM147 antibody can be used for detection of TMEM147 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
TMEM147 Antibody: TMEM147 is a recently identified protein that associates with Nicalin and NOMO, forming a complex that is thought to be similar to the gamma-secretase complex. TMEM147 localizes to the endoplasmic reticulum (ER), and in zebrafish, is expressed during early development. TMEM147 also interacts with the M3 muscarinic receptor (M3R) in the ER and is thought to negatively its expression and function.
Background References:
- Dettmer U, Kuhn PH, Abou-Ajram C, et al. Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex. J. Biol. Chem. 2010; 285:26174-81
- Rosemond E, Rossi M, McMillin SM, et al. Regulation of M3 muscarinic receptor expression and function by transmembrane protein 147. Mol. Pharmacol. 2011; 79:251-61.
Buffer:
TMEM147 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
TMEM147 antibody was raised against a 13 amino acid synthetic peptide near the center of human TMEM147.
The immunogen is located within amino acids 70 - 120 of TMEM147.
The immunogen is located within amino acids 70 - 120 of TMEM147.
NCBI Gene ID #:
10430
NCBI Official Name:
transmembrane protein 147
NCBI Official Symbol:
TMEM147
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_116024
Protein GI Number:
14249166
Purification:
TMEM147 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
Swissprot #:
Q9BVK8
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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