SPATA6 Antibody
| Code | Size | Price |
|---|
| PSI-6555-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6555-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SPATA6 Antibody: HASH, SRF1, SRF-1, Spermatogenesis-associated protein 6
Application Note:
SPATA6 antibody can be used for detection of SPATA6 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
SPATA6 Antibody: The development of spermatogonial stem cells into spermatozoa, i.e., spermatogenesis, is a highly ordered process that requires multiple proteins, including some that are testis-specific or testis-specific isoforms of genes that are expressed in other tissues. One such protein is SPATA6: while its full-length isoform is expressed in multiple tissues including thymus, brain and testis, the shorter isoform is expressed only in testis. It has some homology to the motor domain of kinesin related proteins and with the C. elegans neural calcium sensor protein NCS-2.
Background References:
- Venables JP. Alternative splicing in the testes. Curr. Opin. Genet. Dev. 2002; 12:615-9.
- Oh C, Aho H, Shamsadin R, et al. Characterization, expression pattern and chromosomal localization of the spermatogenesis associated 6 gene (Spata6). Mol. Human Reprod. 2003; 9:321-30.
Buffer:
SPATA6 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
SPATA6 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human SPATA6.
The immunogen is located within amino acids 400 - 450 of SPATA6.
The immunogen is located within amino acids 400 - 450 of SPATA6.
NCBI Gene ID #:
54558
NCBI Official Name:
spermatogenesis associated 6
NCBI Official Symbol:
SPATA6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_061946
Protein GI Number:
9506603
Purification:
SPATA6 Antibody is affinity chromatography purified via peptide column.
Research Area:
Apoptosis
SPECIFICITY:
At least three isoforms of SPATA6 are known to exist; this antibody will detect only the longest two isoforms. SPATA6 antibody is predicted to not cross-react with other SPATA protein family members.
Swissprot #:
Q9NWH7
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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