ANKLE2 Antibody

ProSci
Product Code: PSI-6609
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6609-0.02mg0.02mg£150.00
Quantity:
PSI-6609-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Chicken
Antibody Isotype: IgY
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)

Images

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Western blot analysis of ANKLE2 in human testis tissue lysate with ANKLE2 antibody at (A) 1 and (B) 2 μg/mL.

Western blot analysis of ANKLE2 in human testis tissue lysate with ANKLE2 antibody at (A) 1 and (B) 2 μg/mL.

Further Information

Additional Names:
ANKLE2 Antibody: Lem4, LEMD7, KIAA0692, LEM4, Ankyrin repeat and LEM domain-containing protein 2, LEM domain-containing protein 4
Application Note:
ANKLE2 antibody can be used for detection of ANKLE2 by Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
ANKLE2 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE2 (Ankyrin repeat and LEM domain containing 2) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains three ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. The function of this protein is still under investigation.
Background References:
  • Lee KK and Wilson KL. All in the family: evidence for four new LEM-domain proteins Lem2 (NET-25), Lem3, Lem4 and Lem5 in the human genome. Symp. Soc. Exp. Biol. 2004; 56:329-39
Buffer:
ANKLE2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ANKLE2 antibody was raised against a 19 amino acid synthetic peptide near the center of human ANKLE2.

The immunogen is located within amino acids 280 - 330 of ANKLE2.
NCBI Gene ID #:
23141
NCBI Official Name:
ankyrin repeat and LEM domain containing 2
NCBI Official Symbol:
ANKLE2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 121, 139, 145 kDa

Observed: 121 kDa
Protein Accession #:
AAH43157
Protein GI Number:
148664230
Purification:
ANKLE2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
SPECIFICITY:
Three isoforms of ANKLE2 are known to exist; this antibody will detect all three. ANKLE2 antibody is predicted to not cross-react with ANKLE1.
Swissprot #:
Q86XL3
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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