SPATA19 Antibody
| Code | Size | Price |
|---|
| PSI-6617-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6617-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Isotype: IgY
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SPATA19 Antibody: CT132, SPAS1, spergen1, SPERGEN1, Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein, Spergen-1
Application Note:
SPATA19 antibody can be used for detection of SPATA19 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
SPATA19 Antibody: SPATA19, also known as SPERGEN1, was initially identified as a testis-specific protein that localizes to the surface of mitochondria in the middle piece of mature spermatozoa. Recent experiments have shown that elevated levels of SPATA19 have been found in basal cell carcinomas and prostate cancers, suggesting that SPATA19 may serve as a putative cancer biomarker and a target for cancer immunotherapy.
Background References:
- Miyamoto T, Sengoku K, Hasuike S, et al. Isolation and expression analysis of the human testis-specific gene, SPERGEN-1, a spermatogenic cell-specific gene-1. J. Assist. Reprod. Genet. 2003; 20:101-4.
- Doiguchi M, Mori T, Toshimori K, et al. Spergen-1 might be an adhesive molecule associated with mitochondria in the middle piece of spermatozoa. Dev. Biol. 2002; 252:127-37.
- Ghafouri-Fard S, Abbasi A, Moslehi H, et al. Elevated levels of testis-specific genes TEX101 and SPATA19 in basal cell carcinoma and their correlation with clinical and pathological features. Br. J. Dermatol. 2010; 162:772-9
- Ghafouri-Fard S, Ousati Ashtiani Z, Sabah Golian B, et al. Expression of two testis-specific genes, SPATA19 and LEMD1, in prostate cancer. Arch. Med. Res. 2010; 41:195-200.
Buffer:
SPATA19 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (82%)
Immunogen:
SPATA19 antibody was raised against an 17 amino acid synthetic peptide near the amino terminus of human SPATA19.
The immunogen is located within amino acids 30 - 80 of SPATA19.
The immunogen is located within amino acids 30 - 80 of SPATA19.
NCBI Gene ID #:
219938
NCBI Official Name:
spermatogenesis associated 19
NCBI Official Symbol:
SPATA19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 18 kDa
Observed: 26 kDa
Observed: 26 kDa
Protein Accession #:
EAW67810
Protein GI Number:
28376652
Purification:
SPATA19 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
At least two isoforms of SPATA19 are known to exist; this antibody will detect both isoforms. SPATA19 antibody is predicted to not cross-react with other SPATA family members.
Swissprot #:
Q7Z5L4
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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