MLIP Antibody
| Code | Size | Price |
|---|
| PSI-6719-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6719-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
MLIP Antibody: C6orf142, C6orf142, Muscular LMNA-interacting protein, Muscular-enriched A-type laminin-interacting protein
Application Note:
MLIP antibody can be used for detection of MLIP by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies
Background References:
- Ahmady E, Deeke SA, Rabaa S, et al. Identification of a novel muscle A-type lamin-interacting protein (MLIP). J. Biol. Chem. 2011; 286:19702-13.
Buffer:
MLIP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MLIP antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MLIP.
The immunogen is located within the last 50 amino acids of MLIP.
The immunogen is located within the last 50 amino acids of MLIP.
NCBI Gene ID #:
90523
NCBI Official Name:
muscular LMNA-interacting protein
NCBI Official Symbol:
MLIP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_612636
Protein GI Number:
154426278
Purification:
MLIP Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
At least three isoforms of MLIP are known to exist.
Swissprot #:
Q5VWP3
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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