YPEL2 Antibody
| Code | Size | Price |
|---|
| PSI-6773-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6773-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
YPEL2 Antibody: FKSG4, Protein yippee-like 2
Application Note:
YPEL2 antibody can be used for detection of YPEL2 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
YPEL2 Antibody: YPEL2 (yippee-like 2) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL2 might be an important factor during the development and malignant transformation of tissues, most notably pancreatic and breast tumors.
Background References:
- Hosono K, Sasaki T, Minoshima S, et al. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Gene 2004; 340: 31-43.
- Couch FJ, Wang X, Bamlet WR, et al. Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. Cancer Epidemiol. Biomarkers Prev. 2010; 19:251-7
- Olson JE, Wang X, Pankratz VS, et al. Centrosome-related genes, genetic variation, and risk of breast cancer. Breast Cancer Res. Treat. 2011; 125:221-8.
Buffer:
YPEL2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
YPEL2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human YPEL2.
The immunogen is located within amino acids 30 - 80 of YPEL2.
The immunogen is located within amino acids 30 - 80 of YPEL2.
NCBI Gene ID #:
388403
NCBI Official Name:
yippee-like 2
NCBI Official Symbol:
YPEL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAW94407
Protein GI Number:
53292625
Purification:
YPEL2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q96QA6
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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