RLP2 Antibody
| Code | Size | Price |
|---|
| PSI-6799-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6799-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
RLP2 Antibody: RLP2, RLP2, RILP-like protein 2, Rab-interacting lysosomal protein-like 2
Application Note:
RLP2 antibody can be used for detection of RLP2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
RLP2 Antibody: The Rab interacting lysosomal protein-like 2 (RLP2) protein is related to the is lysosomal protein RILP which interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Little is known of the exact function of RLP2, but it is thought that RILP is a downstream effector of RAB7 and both proteins act together in the regulation of late endocytic traffic, suggesting that RLP2 may be involved in endocytic traffic with RILP or play a similar role. RILP and possible RLP2 may also play a role in the biogenesis of multivesicular bodies.
Background References:
- Wang T, Wong KK, and Hong W. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. Mol. Biol. Cell 2004; 15:815-26.
- Cantalupo G, Alifano P, Roberti V, et al. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J. 2001; 20:683-93.
- Progida C, Spinosa MR, De Luca A, et al. RILP interacts with the VPS22 component of the ESCRT-II complex. Biochem. Biophys. Res. Commun. 2006; 347:1074-9.
Buffer:
RLP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse: (100%), Rat: (100%), Bovine: (100%)
Immunogen:
RLP2 antibody was raised against an 16 amino acid synthetic peptide near the center of human RLP2.
The immunogen is located within amino acids 110 - 160 of RLP2.
The immunogen is located within amino acids 110 - 160 of RLP2.
NCBI Gene ID #:
196383
NCBI Official Name:
Rab interacting lysosomal protein-like 2
NCBI Official Symbol:
RILPL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_659495
Protein GI Number:
21450828
Purification:
RLP2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
Swissprot #:
Q969X0
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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