TFCP2L1 Antibody

ProSci
Product Code: PSI-6807
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6807-0.02mg0.02mg£150.00
Quantity:
PSI-6807-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)

Images

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Western blot analysis of TFCP2L1 in human colon tissue lysate with TFCP2L1 antibody at (A) 1 and (B) 2 μg/mL
2 / 3
Immunohistochemistry of TFCP2L1 in rat colon tissue with TFCP2L1 antibody at 2.5 μg/mL.
3 / 3
Immunofluorescence of TFCP2L1 in rat colon tissue with TFCP2L1 antibody at 20 μg/mL.

Western blot analysis of TFCP2L1 in human colon tissue lysate with TFCP2L1 antibody at (A) 1 and (B) 2 μg/mL
Immunohistochemistry of TFCP2L1 in rat colon tissue with TFCP2L1 antibody at 2.5 μg/mL.
Immunofluorescence of TFCP2L1 in rat colon tissue with TFCP2L1 antibody at 20 μg/mL.

Further Information

Additional Names:
TFCP2L1 Antibody: LBP9, CRTR1, LBP-9, LBP9, Transcription factor CP2-like protein 1, CP2-related transcriptional repressor 1, CRTR-1
Application Note:
TFCP2L1 antibody can be used for detection of TFCP2L1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.

Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
TFCP2L1 Antibody: The Transcription factor CP2-like protein 1 (TFCP2L1) is related to the ubiquitously expressed CP2 family of transcription factors that are generally transcription factors. TFCP2L1 is expressed in a developmentally regulated fashion during embryogenesis and in the epithelial lining of distal convoluted tubules in embryonic and adult kidneys. Recent studies have shown that TFCP2L1 is part of an Oct4-centered protein interaction network in embryonic stem cells. It is thought to modulate the activity of other CP2 family members in a cell specific manner, and is itself regulated by sumoylation at a single major site.
Background References:
  • Rodda S, Sharma S, Scherer M, et al. CRTR-1, a developmentally regulated transcriptional repressor related to the CP2 family of transcription factors. J. Biol. Chem. 2001; 276:3324-32.
  • van den Berg DL, Snoek T, Mullin NP, et al. An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 2010; 6:369-81.
  • To S, Rodda SJ, Rathjen PD, et al. Modulation of CP family transcriptional activity by CRTR-1 and sumoylation. PLoS One 2011; 5:e11702.
Buffer:
TFCP2L1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TFCP2L1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TFCP2L1.

The immunogen is located within the first 50 amino acids of TFCP2L1.
NCBI Gene ID #:
29842
NCBI Official Name:
transcription factor CP2-like 1
NCBI Official Symbol:
TFCP2L1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_055368
Protein GI Number:
7657299
Purification:
TFCP2L1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
Swissprot #:
Q9NZI6
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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