ZNF687 Antibody
| Code | Size | Price |
|---|
| PSI-6067-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6067-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Documents
Further Information
Additional Names:
ZNF687 Antibody: KIAA1441, Zinc finger protein 687
Application Note:
ZNF687 antibody can be used for detection of ZNF687 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
ZNF687 Antibody: The zinc finger protein 687 (ZNF687) was initially identified as a translocation partner gene with RUNX1 in patients with acute myeloid leukemia (AML). Little is known of the function of the ZNF687 protein, but it has been shown to weakly interact with the Ring1/Rnf2 RING finger protein member of the Polycomb group of proteins, suggesting it may be involved in the chromatin-modifying complexes essential for embryonic development and stem cell renewal. Other evidence suggests that ZNF687 may be part of a transcriptional network that also includes ZNF592 and ZMYMD8.
Background References:
- Nguyen TT, Ma LN, Slovak ML, et al. Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTDf2, and ZNF687 in acute myeloid leukemia. Genes Chromo. Cancer 2006; 45:918-32.
- Sanchez C, Sanchez I, Demmers JA, et al. Proteomics analysis of Ring1/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor. Mol. Cell Proteomics 2007; 6:820-34.Malovannaya A, Lanz RB, Jung SY, et al. Analysis of the human endogenous coregulator complexome. Cell 2011; 145:787-99.
Buffer:
ZNF687 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse: (94%)
Immunogen:
ZNF687 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZNF687.
The immunogen is located within the first 50 amino acids of ZNF687.
The immunogen is located within the first 50 amino acids of ZNF687.
NCBI Gene ID #:
57592
NCBI Official Name:
zinc finger protein 687
NCBI Official Symbol:
ZNF687
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_065883
Protein GI Number:
24308227
Purification:
ZNF687 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
ZNF687 antibody is human specific. At least three isoforms of ZNF687 are known to exist; this antibody will detect the the two largest isoforms.
Swissprot #:
Q8N1G0
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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