WDR18 Antibody
| Code | Size | Price |
|---|
| PSI-6817-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-6817-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
WDR18 Antibody: Ipi3, R32184_1, WD repeat-containing protein 18
Application Note:
WDR18 antibody can be used for detection of WDR18 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
WDR18 Antibody: WD repeat domain 18 (WDR18) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WD repeats are minimally conserved regions of approximately 40 amino acids that commonly form a tertiary propeller structure. WDR18 is a 432 amino acid protein that contains six WD repeats and is encoded by a gene located on human chromosome 19. WDR18 may play a role during development. The complex PELP1-TEX10-WDR18 is required for the maturation and nucleolar release of the large ribosomal subunit.
Background References:
- Smith TF, Gaitatzes C, Saxena K, et al. The WD repeat: a common architecture for diverse functions. Trends Biochem. Sci. 1999; 24:181-5.
- Gao W, Xu L, Guan R, et al. Wdr18 is required for Kupffer's vesicle formation and regulation of body asymmetry in zebrafish. PLoS One 2011; 6:e23386.
- Finkbeiner E, Haindl M, and Muller S. The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. EMBO J. 2011; 30:1067-78.
Buffer:
WDR18 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen:
WDR18 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human WDR18.
The immunogen is located within the last 50 amino acids of WDR18.
The immunogen is located within the last 50 amino acids of WDR18.
NCBI Gene ID #:
57418
NCBI Official Name:
WD repeat domain 1
NCBI Official Symbol:
WDR18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_077005
Protein GI Number:
56243583
Purification:
WDR18 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
WDR18 antibody is predicted to not cross-react with other WDR family members.
Swissprot #:
Q9BV38
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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