ZBTB40 Antibody

ProSci
Product Code: PSI-6905
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-6905-0.02mg0.02mg£150.00
Quantity:
PSI-6905-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)

Images

1 / 2
Western blot analysis of ZBTB40 in Raji cell lysate with ZBTB40 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.
2 / 2
Immunofluorescence of ZBTB40 in Raji cells with ZBTB40 antibody at 20 μg/mL.

Western blot analysis of ZBTB40 in Raji cell lysate with ZBTB40 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of ZBTB40 in Raji cells with ZBTB40 antibody at 20 μg/mL.

Further Information

Additional Names:
ZBTB40 Antibody: ZNF923, KIAA0478, Zinc finger and BTB domain-containing protein 40
Application Note:
ZBTB40 antibody can be used for detection of ZBTB40 by Western blot at 0.5 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 5 μg/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
ZBTB40 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB40, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Single nucleotide polymorphisms near ZBTB40 have been linked to differences in bone mineral density of the hip and lumbar spine, and had a significant association with low-trauma fractures suggesting that ZBTB40 may be involved in bone development and formation.
Background References:
  • Filion GJP, Zhenilo S, Salozhin S, et al. A family of zinc finger proteins that bind methylated DNA and repress transcription. Mol. Cell. Biol. 2006; 26:169-81.
  • Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, et al. Multiple genetic loci for bone mineral density and fractures. New Eng. J. Med. 2008; 358:2355-65.
Buffer:
ZBTB40 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ZBTB40 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ZBTB40.

The immunogen is located within amino acids 180 - 230 of ZBTB40.
NCBI Gene ID #:
9923
NCBI Official Name:
zinc finger and BTB domain containing 40
NCBI Official Symbol:
ZBTB40
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_055685
Protein GI Number:
139394556
Purification:
ZBTB40 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
ZBTB40 antibody is human specific. At least two isoforms of ZBTB40 are known to exist. This antibody is predicted to not cross-react with other ZBTB protein family members.
Swissprot #:
Q9NUA8
User NOte:
Optimal dilutions for each application to be determined by the researcher.

Related Products

Product NameProduct CodeSupplier 
ZBTB40 PeptidePSI-6905PProSci Summary Details