SLAIN2 Antibody
| Code | Size | Price |
|---|
| PSI-5471-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-5471-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Documents
Further Information
Additional Names:
SLAIN2 Antibody: KIAA1458, KIAA1458, SLAIN motif-containing protein 2
Application Note:
SLAIN2 antibody can be used for detection of SLAIN2 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
SLAIN2 Antibody: SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
Background References:
- Hirst CE, Ng ES, Azzola L, et al. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev. Biol. 2006; 293:90-103.
- van der Vaart B, Manatschal C, Grigoriev I, et al. SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J. Cell Biol. 2011; 193:1083-99.
Buffer:
SLAIN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (93%)
Immunogen:
SLAIN2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human SLAIN2.
The immunogen is located within amino acids 70 - 120 of SLAIN2.
The immunogen is located within amino acids 70 - 120 of SLAIN2.
NCBI Gene ID #:
57606
NCBI Official Name:
SLAIN motif family, member 2
NCBI Official Symbol:
SLAIN2
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
AAH40993
Protein GI Number:
26454712
Purification:
SLAIN2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
SLAIN2 antibody is predicted not to cross-react with SLAIN1.
Swissprot #:
Q9P270
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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