SHQ1 Antibody
| Code | Size | Price |
|---|
| PSI-7029-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7029-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Western Blot (WB)
Documents
Further Information
Additional Names:
SHQ1 Antibody: Shq1p, Protein SHQ1 homolog
Application Note:
SHQ1 antibody can be used for detection of SHQ1 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
SHQ1 Antibody: SHQ1 is the human homolog of yeast Shq1p, a protein that acts as an accessory factor in the assembly of H/ACA ribonucleoproteins. SHQ1 has been shown to bind the major H/ACA core protein and the pseudouridine synthase NAP57, but precedes the assembly role of NAF1 and of the other H/ACA core proteins. SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase.
Background References:
- Ito T, Chiba T, Ozawa R, et al. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc. Natl. Acad. Sci. USA 2001; 98:4569-74.
- Grozdanov PN, Roy S, Kittur N, et al. SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs. RNA 2009; 15:1188-97.
Buffer:
SHQ1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (94%)
Immunogen:
SHQ1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SHQ1.
The immunogen is located within amino acids 80 - 130 of SHQ1.
The immunogen is located within amino acids 80 - 130 of SHQ1.
NCBI Gene ID #:
55164
NCBI Official Name:
SHQ1 homolog (S. cerevisiae)
NCBI Official Symbol:
SHQ1
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
NP_060600
Protein GI Number:
56550033
Purification:
SHQ1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
Multiple isoforms are known to exist.
Swissprot #:
Q6PI26
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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