TNFAIP2 Antibody
| Code | Size | Price |
|---|
| PSI-7051-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7051-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TNFAIP2 Antibody: B94, EXOC3L3, Tumor necrosis factor alpha-induced protein 2, Primary response gene B94 protein, TNF alpha-induced protein 2
Application Note:
TNFAIP2 antibody can be used for detection of TNFAIP2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
TNFAIP2 Antibody: TNFAIP2, also known as B94, is a TNF-a-regulated gene that is expressed in endothelial cells, peripheral blood cells, and mature sperm. Recently, elevated TNFAIP2 expression was observed in nasopharyngeal carcinoma, and high expression of TNFAIP2 was significantly correlated with higher levels of cell migration, invasion and metastasis, suggesting that TNFAIP2 may serve as a useful prognostic indicator for nasopharyngeal carcinoma. TNFAIP2 has also been implicated as part of the viral-sensing circuit of the innate immune response.
Background References:
- Wolf FW, Sarma V, Deldin M, et al. B94, a primary response gene inducible by tumor necrosis factor-alpha, is expressed in developing hematopoietic cells and the sperm acrosome. J. Biol. Chem. 1994; 269:3633-40.
- Chen LC, Chen CC, Liang Y, et al. A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma. Mod. Pathol. 2011; 24:175-84.
- Chevrier N, Mertins P, Artyomov MN, et al. Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell 147:853-67.
Buffer:
TNFAIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TNFAIP2 antibody was raised against a 19 amino acid synthetic peptide near the center of human TNFAIP2.
The immunogen is located within amino acids 330 - 380 of TNFAIP2.
The immunogen is located within amino acids 330 - 380 of TNFAIP2.
NCBI Gene ID #:
7127
NCBI Official Name:
tumor necrosis factor, alpha-induced protein 2
NCBI Official Symbol:
TNFAIP2
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
NP_006282
Protein GI Number:
26051240
Purification:
TNFAIP2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
SPECIFICITY:
At least two isoforms of TNFAIP2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with TNFAIP3.
Swissprot #:
Q03169
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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