FOXH1 Antibody
| Code | Size | Price |
|---|
| PSI-7095-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7095-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Western Blot (WB)
Documents
Further Information
Additional Names:
FOXH1 Antibody: FAST1, FAST-1, FAST1, FAST2, Forkhead box protein H1, Forkhead activin signal transducer 1, Fast-1
Application Note:
FOXH1 antibody can be used for detection of FOXH1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
FOXH1 Antibody: FOXH1 is a member of the Forkhead-box (FOX) family of transcription factors and is the human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 plays an important role in mediating TGF-beta/activin signals through its interaction with the SMAD2-SMAD4 complex. It is expressed primarily during early development and localizes in the cytoplasm until it forms a complex with the SMAD proteins at which time it translocates to the nucleus to positively or negatively affect gene expression.
Background References:
- Chen X, Weisberg E, Fridmacher V, et al. Smad and FAST-1 in the assembly of activin-responsive factor. Nature 1997; 389:85-9.
- Zhou S, Zewel L, Lengauer C, et al. Characterization of human FAST-1, a TGF beta and activin signal transducer. Mol. Cell 1998; 2:121-7.
- Attisano L, Silvestri C, Izzi L, et al. The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signaling. Mol. Cell. Endocrinol. 2001; 180:3-11.
Buffer:
FOXH1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Rabbit polyclonal FOXH1 antibody was raised against a 19 amino acid peptide near the amino terminus of human FOXH1.
The immunogen is located within the first 50 amino acids of FOXH1.
The immunogen is located within the first 50 amino acids of FOXH1.
NCBI Gene ID #:
8928
NCBI Official Name:
forkhead box H1
NCBI Official Symbol:
FOXH1
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
NP_003914
Protein GI Number:
4503657
Purification:
FOXH1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
FOXH1 antibody is predicted to not cross-react with any other members of the forkhead box family.
Swissprot #:
O75593
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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