TRPV1 Antibody
| Code | Size | Price |
|---|
| PSI-7179-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7179-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
TRPV1 Antibody: VR1, VR1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, TrpV1
Application Note:
TRPV1 antibody can be used for detection of TRPV1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
TRPV1 Antibody: TRPV1 is a receptor for capsaicin, the main pungent ingredient in hot chili peppers, and elicits a sensation of burning pain by selectively activating sensory neurons. TRPV1 is a non-selective cation channel that is structurally related to members of the TRP family of ion channels such as TRPC3 and TRPC6. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.
Background References:
- Eid SR and Cortright DN. Transient receptor potential channels on sensory nerves. Handb. Exp. Pharmacol. 2009; 194:261-81.
- Minke B and Cook B. TRP channel proteins and signal transduction. Physiol. Rev. 2002; 82:429-72.
- Planells-Cases R, Valente P, Ferrer-Montiel A, et al. Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention. Adv. Exp. Med. Biol. 2011; 704:491-515.
Buffer:
TRPV1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Guinea pig: (81%), Mouse: (75%)
Immunogen:
Rabbit polyclonal TRPV1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TRPV1.
The immunogen is located within the last 50 amino acids of TRPV1.
The immunogen is located within the last 50 amino acids of TRPV1.
NCBI Gene ID #:
7442
NCBI Official Name:
transient receptor potential cation channel, subfamily V, member 1
NCBI Official Symbol:
TRPV1
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 92 kDa
Protein Accession #:
NP_542437
Protein GI Number:
74315354
Purification:
TRPV1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
Swissprot #:
Q8NER1
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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