HIV-1 p24 Antibody

ProSci
Product Code: PSI-7313
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-7313-0.02mg0.02mg£150.00
Quantity:
PSI-7313-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)

Images

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Western blot analysis of p24 using p24 antibody at 0.5 μg/mL to detect (A) 2 ng and (B) 10 ng of recombinant HIV-1 p24.

Western blot analysis of p24 using p24 antibody at 0.5 μg/mL to detect (A) 2 ng and (B) 10 ng of recombinant HIV-1 p24.

Further Information

Additional Names:
HIV-1 p24 Antibody: Gag polyprotein, Pr55Gag, MA
Application Note:
P24 antibody can be used for detection of p24 by Western blot at 0.5 - 1 μg/mL.
Background:
HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.
Background References:
  • Goto T, Nakai M, and Ikuta K. The life-cycle of human immunodeficiency virus type 1. Micron 1998; 29:123-38.
  • Freed EO. HIV-1 gag proteins: diverse functions in the virus life cycle. Virology 1998; 251:1-15.
  • Lindenburg CE, Stolte I, Langendam MW, et al. Long-term follow-up : no effect of therapeutic vaccination with HIV-1 p17/p24:Ty virus-like particles on HIV-1 disease progression. Vaccine 2002 ; 20 :2343-7.
Buffer:
HIV-1 p24 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Rabbit polyclonal HIV-1 p24 antibody was raised against a recombinant full-length HIV-1 p24 protein .
NCBI Gene ID #:
155030
NCBI Official Name:
gag Pr55(Gag)
NCBI Official Symbol:
GAG
NCBI Organism:
hiv-1
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
AAB50258
Protein GI Number:
327745
Purification:
HIV-1 p24 Antibody is Protein A purified.
Research Area:
Infectious Disease
SPECIFICITY:
P24 antibody detects a 24 kDa recombinant protein.
Swissprot #:
P04591
User NOte:
Optimal dilutions for each application to be determined by the researcher.