MTERFD3 Antibody
| Code | Size | Price |
|---|
| PSI-7285-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7285-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
MTERFD3 Antibody: mTERF2, mTERFL, mTERF domain-containing protein 3, mitochondrial, Mitochondrial transcription termination factor 2, mTERF2
Application Note:
MTERFD3 Antibody can be used for detection of MTERFD3 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Background:
MTERFD3 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD3 was initially identified through differential display analysis and is expressed primarily in heart, liver, pancreas and skeletal muscle. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription, and may be a serum-inhibitory factor.
Background References:
- Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79.
- Chen Y, Zhou G, Yu M, et al. Cloning and functional analysis of human mTERFL encoding a novel mitochondrial transcription termination factor-like protein. Biochem. Biophys. Res. Commun. 2005; 337:1112-8.
- Park CB, Asin-Cayuela J, Camara Y, et al. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell 2007; 130:273-85.
Buffer:
MTERFD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat: (76%)
Immunogen:
MTERFD3 antibody was raised against an 18 amino acid peptide near the amino terminus of human MTERFD3 .
The immunogen is located within amino acids 20 - 70 of MTERFD3.
The immunogen is located within amino acids 20 - 70 of MTERFD3.
NCBI Gene ID #:
80298
NCBI Official Name:
MTERF domain containing 3
NCBI Official Symbol:
MTERFD3
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 42 kDa
Observed: 40 kDa
Observed: 40 kDa
Protein Accession #:
NP_079474
Protein GI Number:
21314736
Purification:
MTERFD3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
SPECIFICITY:
MTERFD3 antibody is predicted to not cross-react with other MTERFD protein family members.
Swissprot #:
Q49AM1
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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