PRRT2 Antibody
| Code | Size | Price |
|---|
| PSI-7295-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7295-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
PRRT2 Antibody: PKC, EKD1, ICCA, BFIC2, BFIS2, DSPB3, DYT10, FICCA, IFITMD1, Proline-rich transmembrane protein 2, Dispanin subfamily B member 3
Application Note:
PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
PRRT2 Antibody: The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.
Background References:
- Wang JL, Cao L, Li XH, et al. Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias. Brain 2011; 134:3493-501.
- Scheffer IE, Grinton BE, Heron SE, et al. PRRT2 phenotypic spectrum includes sporadic and fever-related infantile seizures. Neurology 2012; epub.
Buffer:
PRRT2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PRRT2 antibody was raised against a 18 amino acid peptide near the center of human PRRT2 .
The immunogen is located within amino acids 180 - 230 of PRRT2.
The immunogen is located within amino acids 180 - 230 of PRRT2.
NCBI Gene ID #:
112476
NCBI Official Name:
proline-rich transmembrane protein 2
NCBI Official Symbol:
PRRT2
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 43 kDa
Observed: 44 kDa
Observed: 44 kDa
Protein Accession #:
NP_001243371
Protein GI Number:
374253783
Purification:
PRRT2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
Multiple isoforms of PRRT2 are known to exist.
Swissprot #:
Q7Z6L0
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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