CNRIP1 Antibody
| Code | Size | Price |
|---|
| PSI-7303-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7303-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
CNRIP1 Antibody: CRIP1, C2orf32, CB1 cannabinoid receptor-interacting protein 1, CRIP-1
Application Note:
CNRIP1 antibody can be used for detection of CNRIP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Background:
CNRIP1 Antibody: The CNRIP1 (cannabinoid receptor interacting protein 1) protein is a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1 (CB1) and is thought to play a role in synaptic plasticity, analgesia, appetite, and neuroprotection. One isoform of CNRIP1, CNRIP1a, modulates the constitutive CB1 receptor activity in the central nervous system (CNS), while the role of the shorter isoform CNRIP1b is yet unknown. CNRIP1 has been suggested as a potential target for CNS drug discovery.
Background References:
- Niehaus JL, Liu Y, Wallis KT, et al. CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a. Mol. Pharmacol. 2007; 72:1557-66.
- Smith TH, Sim-Selley LJ, and Selley DE. Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery. Br. J. Pharm. 2010; 160:454-66.
Buffer:
CNRIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (93%)
Immunogen:
CNRIP1 antibody was raised against a 15 amino acid peptide near the center of human CNRIP1.
The immunogen is located within amino acids 50 - 100 of CNRIP1.
The immunogen is located within amino acids 50 - 100 of CNRIP1.
NCBI Gene ID #:
25927
NCBI Official Name:
cannabinoid receptor interacting protein 1
NCBI Official Symbol:
CNRIP1
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 18 kDa
Observed: 16 kDa
Observed: 16 kDa
Protein Accession #:
NP_056278
Protein GI Number:
24308071
Purification:
CNRIP1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
SPECIFICITY:
At least two isoforms of CNRIP1 are known to exist; this antibody will detect both isoforms.
Swissprot #:
Q96F85
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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