Rift Valley Fever Virus Nucleocapsid Antibody

ProSci
Product Code: PSI-7413
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-7413-0.02mg0.02mg£150.00
Quantity:
PSI-7413-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)

Further Information

Additional Names:
Rift Valley Fever Virus Nucleocapsid Antibody:
Application Note:
RVF virus nucleocapsid antibody can detect 10ng RVF virus nucleocapsid peptide in ELISA at 1 μg/mL.
Background:
Rift Valley Fever Virus Nucleocapsid Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes (1). During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity (2). The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins (3).
Background References:
  • Morrill JC and McClain DJ. Epidemiology and pathogenesis of the Rift Valley fever and other phleboviruses, p. 281-93 in H Fraenkel-Conrat and RR Wagner (ed.) The viruses. Plenum Press, New York, NY.
  • Schmaljohn C and Hooper JW. Bunyaviridae: the viruses and their replication, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
  • Giorgi C, Accardi L, Nicoletti M, et al. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian sandfly fever, and Uukuniemi viruses. Virology 1991; 180:738-53.
Buffer:
Rift Valley Fever Virus Nucleocapsid Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
RVF virus nucleocapsid antibody was raised against a 17 amino acid peptide near the center of the RVF virus nucleocapsid.

The immunogen is located within amino acids 70 - 120 of Rift Valley Fever Virus Nucleocapsid.
NCBI Gene ID #:
9538291
NCBI Official Name:
NP nucleocapsid [ Rift Valley fever virus ]
NCBI Official Symbol:
NP
NCBI Organism:
Rift Valley fever virus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 27 kDa
Protein Accession #:
YP_003848707
Protein GI Number:
302596926
Purification:
Rift Valley Fever Virus Nucleocapsid Antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
Q9QKA6
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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