Rift Valley Fever Virus Polymerase Antibody
| Code | Size | Price |
|---|
| PSI-7415-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7415-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Documents
Further Information
Additional Names:
Rift Valley Fever Virus Polymerase Antibody:
Application Note:
RVF virus Polymerase antibody can detect 10 ng RVF virus Polymerase peptide in ELISA at 1 μg/mL.
Background:
Rift Valley Fever Virus Polymerase Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes (1). During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity (2). The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins (3).
Background References:
- Morrill JC and McClain DJ. Epidemiology and pathogenesis of the Rift Valley fever and other phleboviruses, p. 281-93 in H Fraenkel-Conrat and RR Wagner (ed.) The viruses. Plenum Press, New York, NY.
- Schmaljohn C and Hooper JW. Bunyaviridae: the viruses and their replication, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
- Giorgi C, Accardi L, Nicoletti M, et al. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian sandfly fever, and Uukuniemi viruses. Virology 1991; 180:738-53.
Buffer:
RVF virus Polymerase Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
RVF virus Polymerase antibody was raised against a 16 amino acid peptide near the amino terminus of the RVF virus Polymerase.
The immunogen is located within amino acids 370 - 420 of Rift Valley Fever Virus Polymerase.
The immunogen is located within amino acids 370 - 420 of Rift Valley Fever Virus Polymerase.
NCBI Gene ID #:
9538294
NCBI Official Name:
RVFV_sL_gp1 polymerase [ Rift Valley fever virus ]
NCBI Official Symbol:
RVFV_sL_gp1
NCBI Organism:
Rift Valley fever virus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 230 kDa
Protein Accession #:
ABD51508
Protein GI Number:
88770008
Purification:
Rift Valley Fever Virus Polymerase Antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
A2SZS2
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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