PPFIA3 Antibody
| Code | Size | Price |
|---|
| PSI-7561-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7561-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Documents
Further Information
Additional Names:
PPFIA3 Antibody: LPNA3, KIAA0654, Liprin-alpha-3, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3, PTPRF-interacting protein alpha-3
Application Note:
PPFIA3 antibody can be used for detection of PPFIA3 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development (1). Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones (2).
Background References:
- Serra-Pages C, Medley QG, Tang M, et al. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 1998; 273:15611-20.
- Ko J, Na M, Kim S, et al. Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. J. Biol. Chem. 2003; 278:42377-85.
Buffer:
PPFIA3 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PPFIA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PPFIA3.
The immunogen is located within amino acids 1100 - 1150 of PPFIA3.
The immunogen is located within amino acids 1100 - 1150 of PPFIA3.
NCBI Gene ID #:
8541
NCBI Official Name:
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
NCBI Official Symbol:
PPFIA3
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 131 kDa
Observed: 131 kDa
Observed: 131 kDa
Protein Accession #:
NP_003651
Protein GI Number:
32189362
Purification:
PPFIA3 antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
SPECIFICITY:
PPFIA3 antibody is human, mouse, and rat reactive.
Swissprot #:
O75145
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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