TMIGD2 Antibody

ProSci
Product Code: PSI-7617
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-7617-0.02mg0.02mg£150.00
Quantity:
PSI-7617-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)

Images

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Western blot analysis of TMIGD2 in mouse small intestine tissue lysate with TMIGD2 antibody at 1 μg/ml.
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Immunohistochemistry of TMIGD2 in human small intestine tissue with TMIGD2 antibody at 5 μg/mL.

Western blot analysis of TMIGD2 in mouse small intestine tissue lysate with TMIGD2 antibody at 1 μg/ml.
Immunohistochemistry of TMIGD2 in human small intestine tissue with TMIGD2 antibody at 5 μg/mL.

Further Information

Additional Names:
TMIGD2 Antibody: IGPR1, IGPR-1, IGPR1, UNQ3059/PRO9879, Transmembrane and immunoglobulin domain-containing protein 2, Immunoglobulin and proline-rich receptor 1
Application Note:
TMIGD2 antibody can be used for detection of TMIGD2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Background:
TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins (1). TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration (1).
Background References:
  • Rahimi N, Rezazadeh K, Mahoney JE, et al. Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis. Mol. Biol. Cell 2012; 23:1646-56.
Buffer:
TMIGD2 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TMIGD2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TMIGD2.

The immunogen is located within the last 50 amino acids of TMIGD2.
NCBI Gene ID #:
126259
NCBI Official Name:
transmembrane and immunoglobulin domain containing 2
NCBI Official Symbol:
TMIGD2
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 31 kDa

Observed: 26 kDa
Protein Accession #:
NP_653216
Protein GI Number:
281306838
Purification:
TMIGD2 antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
TMIGD2 antibody is human and mouse reactive. At least three isoforms of TMIGD2 are known to exist; this antibody will detect all three. TMIGD2 antibody is predicted to not cross-react with TMIGD1.
Swissprot #:
Q96BF3
User NOte:
Optimal dilutions for each application to be determined by the researcher.

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