Sin Nombre Virus Nucleocapsid Antibody
| Code | Size | Price |
|---|
| PSI-7685-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7685-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Documents
Further Information
Additional Names:
Sin Nombre Virus Nucleocapsid Antibody:
Application Note:
Sin Nombre virus nucleocapsid antibody can detect 10ng Sin Nombre virus nucleocapsid peptide in ELISA at 1 μg/ml.
Background:
Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). The hantavirus nucleocapsid protein plays several roles in viral replication and assembly, and is the major antigen in humoral responses in humans and mice (2). Within the bunyviridae family, the nucleocapsid protein also functions as an RNA chaperone facilitating the formation of the stable genomic RNA ?panhandle? and is thought to aid in the replication of bunyavirus RNA (3).
Background References:
- Spiropoulou CF, Morzunov S, Feldmann H, et al. Genome structure and variability of a virus causing hantavirus pulmonary syndrome. Virology 1994; 200:715-23.
- Tischler ND, Rosemblatt M, and Valenzuela PD. Characterization of cross-reactive and serotype-specific epitopes on the nucleocapsid proteins of hantaviruses. Virus Res. 2008; 135:1-9.
- Mir MA and Panganiban AT. The bunyavirus nucleocapsid protein is an RNA chaperone: possible roles in viral RNA panhandle formation and genome replication. RNA 2006; 12:272-82.
Buffer:
Sin Nombre virus nucleocapsid antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Sin Nombre virus nucleocapsid antibody was raised against a 19 amino acid peptide near the center of the Sin Nombre virus nucleocapsid.
The immunogen is located within amino acids 170 - 220 of Sin Nombre Virus Nucleocapsid.
The immunogen is located within amino acids 170 - 220 of Sin Nombre Virus Nucleocapsid.
NCBI Gene ID #:
2943142
NCBI Official Name:
SNVsSgp1 nucleocapsid
NCBI Official Symbol:
SNVsSgp1
NCBI Organism:
Sin Nombre virus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
N/A
Protein Accession #:
AAG03030
Protein GI Number:
9944924
Purification:
Sin Nombre virus nucleocapsid antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
Q9E1J8
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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