Puumala Virus Nucleocapsid Antibody
| Code | Size | Price |
|---|
| PSI-7693-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-7693-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Documents
Further Information
Additional Names:
Puumala Virus Nucleocapsid Antibody: Nucleoprotein, Nucleocapsid protein, Protein N
Application Note:
Puumala virus nucleocapsid antibody can detect 10ng Puumala virus nucleocapsid peptide in ELISA at 1 μg/ml.
Background:
Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus (1). Like other hantaviruses, the PUUV glycoprotein is synthesized as a precursor that is posttranslationally processed into two glycoproteins G1 (Gn) and G2 (Gc). These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle (2).
Background References:
- Vapalahti O, Kallio-Kokko H, Salonen EM, et al. Cloning and sequencing of Puumala virus Sotkamo strain S and M RNA segments: evidence for strain variation in hantaviruses and expression of the nucleocapsid protein. J. Gen. Virol. 1992; 73:829-38.
- Hepojoki J, Strandin T, Wang H, et al. Cytoplasmic tails of hantavirus glycoproteins interact with the nucleocapsid protein. J. Gen. Virol. 2010; 91:2341-50.
Buffer:
Puumala virus nucleocapsid antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Puumala virus nucleocapsid antibody was raised against a 19 amino acid peptide near the amino terminus of the Puumala virus nucleocapsid.
The immunogen is located within amino acids 130 - 180 of Puumala Virus Nucleocapsid.
The immunogen is located within amino acids 130 - 180 of Puumala Virus Nucleocapsid.
NCBI Gene ID #:
2943083
NCBI Official Name:
PUUVsSgp1
NCBI Official Symbol:
PUUVsSgp1
NCBI Organism:
Puumala virus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
N/A
Protein Accession #:
ABO93592
Protein GI Number:
144228123
Purification:
Puumala virus nucelocapsid antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
P27313
User NOte:
Optimal dilutions for each application to be determined by the researcher.
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